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Obesity Pharmacotherapy: Current Perspectives and Future Directions - PMC

Evidence ranges from early laboratory work to clinical trials depending on the use — the sections below cover the actual data and sources

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The hypothalamic–pituitary–gonadal (HPG) axis, commonly referred to as the hypothalamic–pituitary ovarian (HPO) axis in women-, underlies these cyclical hormonal changes by coordinating the production of E2 and P4 across the menstrual cycle

and skin or coat abnormalities