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Researchers using clinical samples showed that autophagy was inhibited in patients with high expression of G6PD and ADRB2, or low expression of PTEN and FAT4, contributing to the resistance to lapatinib, 57 sorafenib, 58 trastuzumab 59 and ceritinib, 60 through degradation of HIF1α or promoting epithelial–mesenchymal transition

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[DOI] [PubMed] [Google Scholar] 18.Wei T., Thakur S.S., Liu M., Wen J