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A Mitochondria-Targetable Fluorescent Probe for Dual-Channel NO Imaging Assisted by Intracellular Cysteine and Glutathione | Chem-Station Int. Ed.

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PGC-1α is considered a key transcriptional coactivator for mitochondrial biogenesis, cooperating with various nuclear transcription factors to promote mtDNA replication, mitochondrial protein expression, and maintenance of oxidative phosphorylation capacity (69)