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Firstly, DSDA (1.2 mmol), 1,4-butanediol diacrylate (4.8 mmol), and dichloromethane (5 mL) were mixed into the dry double-necked round-bottomed flask with a thermometer, a container for condensing, dropping funnel, and stirred for 1 min
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It has been found to inhibit the catalytic cysteine of glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH), thereby down-regulating aerobic glycolysis in activated myeloid and lymphoid cells, altering the phenotype of macrophages (145)
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