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Figure 4 3.6 CB-839 alone has limited effects on primary CLL cells To evaluate the effect of CB-839 monotherapy on primary CLL cells, lymphocytes were isolated from 11 patient samples and incubated with 100 nM, 1 μM, 3 μM, and 5 μM of CB-839 for 24 hours

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Neuropathy risks post surgery primarily stem from nutritional deficiencies, notably vitamin B 1 , B 6 , and B 12 , with 4.6% to 16% of patients experiencing neurological symptoms [42]