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Phenotypic and genotypic characteristics of cryopyrin-associated periodic syndrome: a series of 136 patients from the Eurofever Registry
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Because it fails to reach the PARL cleavage system, resulting in full-length PINK1 stabilization and accumulation on the outer mitochondrial membrane, serving as a critical molecular tag that recruits Parkin to initiate clearance of damaged mitochondria and help maintain cellular homeostasis during post-exercise recovery (Quinn et al., 2020
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