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Pull-down assays (co-IPs, etc.) – The Bumbling Biochemist
These are known as third-line antioxidants
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This idea is supported by the strong inverse correlation found between CTR1 levels and myelin content in areas of active MS lesions and the direct correlation between CTR1 or ATP7B and astrogliosis, in as well as the upregulation of all copper transporters in chronic inactive lesions, with high levels of CTR1 and AT7B on GFAP-positive astrocytes in human brain samples
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