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Platinum-induced neurotoxicity is thought to be secondary to the accumulation of platinum within the dorsal root ganglion 7,8
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NAC and FOXO1 inhibitor rescued apoptosis and autophagy induced by cholesterol, the autophagy inhibitor 3-methyladenine (3-MA) enhanced apoptosis, while the apoptosis inhibitor Z-VAD-FMK diminished cholesterol-induced autophagy
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