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This is due, in part, to their specialized function of producing melanin (which generates by-products such as O2− and H2O2) and inflammation due to excessive photo exposure.47,48 In the hair follicle, the outer sheath melanocytes are responsible for intense melanin synthesis
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Protracted oxidative stress and diminished antioxidant defenses are associated with GSH oxidation and depletion (16), a phenomenon observed in hypertensive subjects compared to non-hypertensive subjects (17)
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