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Seven highly effective EGFR binding ligands have been identified to trigger such canonical downstream effects: EGF, transforming growth factor-α (TGF-α), heparin-binding epidermal growth factor (HB-EGF), amphiregulin (AREG), betacellulin, epiregulin, and epigen [179]
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Reuptake inhibitor of serotonin, noradrenaline, and dopamine Tesofensine increases monoaminergic transmission by inhibiting the neuronal uptake of serotonin, dopamine, and noradrenaline, thus causing appetite suppression
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