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The majority of patients (67%) with CGD harbor mutations in an X-chromosome gene (CYBB) that encodes the β-subunit (gp91-PHOX) of cytochrome b 558
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The levels of ferroptotic death vary with the levels of susceptibility according to the distinct states of latency, with Burkitt´s lymphoma cells being highly vulnerable to ROS-induced lipid peroxidation and, consequently, to ferroptosis [74]
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