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Whether nutritional interventions aiming at increasing the levels of vitamin E and vitamin C, both present within foods, may help in restoring an optimal functionality of the antioxidant network have not investigated yet but it can be expected

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In addition to the PubMed literature search, the FDA Multidiscipline and Clinical Pharmacology Review per ADC were examined, as they often provide more unpublished bioanalytical method information than the EMA approval documents