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Cationic CS hydrogels can interact with negatively charged blood cells to promote coagulation (Xu et al., 2013) and hemostasis can be achieved through Ca 2+ activation of thrombin, significantly improving the hemostatic properties (Weng et al., 2022)

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For the assessment of amino acid selectivity of these electrophiles, we implemented an LC-MS/MS-based assay 37 utilizing a nonapeptide (KGDYHFPIC) having multiple nucleophilic residues (Cys, Lys, Tyr)