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DNA-PK functions redundantly with SMG1 to activate NRF2 under mild oxidative stress Because phosphorylation of the SQ motifs at NRF2-S13 and -S40 is critical for NRF2 accumulation, we next examined whether other phosphatidylinositol 3-kinase–related kinases (PIKKs) function redundantly with SMG1

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[DOI] [PubMed] [Google Scholar] 45.Ajoolabady A., Wang S., Kroemer G., Penninger J.M., Uversky V.N., Pratico D., Henninger N., Reiter R.J., Bruno A., Joshipura K., Aslkhodapasandhokmabad H., Klionsky D.J., Ren J