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The use of supplements to support performance and overall health has become increasingly common among athletes and active individuals. One of the most frequent questions we receive is whether a supplement is

5-amino-1MQ acts as an inhibitor of an enzyme called NNMT that degrades a nicotinamide adenine dinucleotide (NAD+) precursor called nicotinamide, which is also a precursor of nicotinamide mononucleotide (NMN)

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Actionable Insights (with effect sizes) For a scientifically literate self-experimenter, the honest take-home is that this is a mechanism paper, not a health-outcome paper — no human or animal was dosed and followed for any clinical endpoint