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PDGF-loaded microneedles promote tendon healing through p38/cyclin D1 pathway mediated angiogenesis - ScienceDirect
Pathophysiology The pathophysiology of eosinophilia is complex and involves the oversecretion and action of cytokines, mainly interleukin-5 (IL-5), the main growth factor of eosinophils
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Because cancer cells rely on constitutively elevated SMG1/NRF2 signaling because of chronic oncogenic ROS production, a condition not equivalently sustained in normal tissues, pharmacological SMG1 inhibition may preferentially compromise tumor cell redox buffering while sparing normal cells that engage this axis only transiently
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