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These perturbations precipitate metabolic programming, contributing to adiposity, skeletal dysregulation, and impaired immune maturation (80)
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LEF-1 staining significantly correlated with CTNNB1 staining (R 2 = 0.1283, p= 0.0046), although with discrepancies at the individual sample level as these were not consecutive slides of the tumour ( Figure 3S )
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