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Oxidative stress This descriptor points to the threat from an unusually high concentration of reactive oxygen species (ROS), of which many are free radicals (ie
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4.2.1 Neuroinflammation after surgery Surgical trauma induces a rise in pro-inflammatory cytokines (IL-6, TNF-α) that can cross the blood-brain barrier or signal via vagal pathways to activate brain endothelium and microglia (68, 72)
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