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HbA 1c Haemoglobin A 1c (HbA 1c ) is a glycated haemoglobin — a measurement used for the assessment of glycaemic control

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While we have not directly tested the impact of ALPS2 motif phosphorylation on GAP activity, especially since the GAP domain is distant and oppositely resides in the N-terminal region of ArfGAP1, a prior study demonstrated that LRRK2-mediated phosphorylation impaired ArfGAP1-stimulated Arf1 GTP hydrolysis in vitro ( in vitro , implying that it was fully functional ( 3 ) for polar side chains at these three sites in the polar face of ALPS2 could similarly alter membrane binding dynamics, yet without impacting the specificity for Golgi-derived vesicles