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Disruption of cysteine uptake and collapse of intracellular GSH pool induces an inhibition of the detoxifying activity of GPx4 and excessive accumulation of oxidatively damaged lipids at the membrane, although it remains unclear if this solely affects the cell plasma membrane, or the effect also extends to organelle membranes

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Previous trials comparing the effect of vitamin B 12 and methylcobalamin showed that the benefit of methylcobalamin was greater than the benefit of vitamin B 12 in patients with Bell’s palsy