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Statistical analysis was conducted utilizing the R program and the epicalc package (version 3.4.3, R Foundation for Statistical Computing, Austria)

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Most studies have supported the use of intravenous STS at a dosage of 25 g (two 12.5 g vials diluted in 100 cc of normal saline) during the last hour of hemodialysis, three times per week, and some suggest that 12.5 g per 100 cc of normal saline be used initially over a one-hour infusion as a test dose initially and, if tolerated, proceed to 25 g [23,24,148,149,150,151,152,153,154,155,156,157,158,159,160,161,162]