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In parallel, excessive Cu + generated in GSH-rich reductive environments can bind lipoylated mitochondrial TCA-cycle proteins such as DLAT, inducing aberrant protein aggregation and triggering cuproptosis across multiple cancer types 187,189,192-194
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[DOI] [PMC free article] [PubMed] [Google Scholar] 26.Baranano DE, Rao M, Ferris CD, Snyder SH
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