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cell signaling research
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The activation of VEGFR-2 and dissociation from VE-cadherin is regulated by a Src-dependent process that can be induced by tensile strains on pulmonary artery ECs ( Models to Study VEGFR-2 Signaling As it is highly difficult to control independent biomechanical forces in in vivo models, most of what we know about VEGFR-2 mechanotransduction comes from in vitro systems
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