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Chemical Synthesis of Gut Microbe-Targeted Choline TMA Lyase Inhibitors The small molecule choline TMA lyase inhibitors iodomethylcholine (IMC) and fluoromethylcholine (FMC) have been previously described as potent and selective mechanism-based inhibitors targeted microbial CutC 27
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Toxin exposure can cause oxidative stress in hepatocytes, leading to the generation of reactive oxygen species (ROS) and oxidative stress
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