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Consequently, further studies of this disease examining the involvement of immune responses in the development and promotion of anemia during canine babesiosis, with a focus on the roles of cytokines and chemokines that mediate these responses, will further our understanding of this disease

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Most recently, metformin, the first-line treatment for type 2 diabetes, was reported to exacerbate acute kidney injury by ferroptosis provoked NETosis in an iron-dependent manner through the binding of CD184 receptor to the Ngal-metformin-Fe complex [189]