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Microglial macrophage-derived ds-HMGB1 in DRG orchestrates neuropathic pain through immune-neural signaling - ScienceDirect
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Vitamin C supplements
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With prolonged exposure or high doses, it transitions to a Phase II block, involving both pre- and post-synaptic effects, including impaired acetylcholine release (autoreceptor inhibition) and open-channel block
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