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melanotan tpeptide positives Skin doctors are urging patients who may be worried after using unregulated peptides to book a skin check. Reporting by national health equity reporters Rachel Carbonell and Caitlyn Gribbin, ABC Specialist Reporting UV Bright Pro
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The melanocortin system is a highly interconnected regulatory network — MC4R-mediated energy balance signalling through the hypothalamic leptin-POMC-MC4R axis intersects with MC3R autoreceptor biology on POMC neurons (MC3R activation reducing POMC neuron firing — negative feedback on the melanocortin output), MC1R-mediated anti-inflammatory biology in peripheral immune cells, and MC5R-driven exocrine gland regulation
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