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The involvement of oxidative stress in tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in HeLa cells

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Subsequently, STATs are phosphorylated and translocated into the nucleus, where they enhance the transcription of target genes (including TGF-β , TNF-α , IL-2 , IL-6 , IL-8 , MMP9 , Intercellular Adhesion Molecule 1 ( ICAM-1 / CD54 ), STAT1 , and STAT3 ) (81)