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For this purpose, it could be noteworthy to functionally validate its possible role on PsA depression and anxiety as a described comorbidity 80 considering also that the tryptophan-kynurenine metabolism has been proposed as a gut-brain link for depression in IBD, itself comorbidity of PsA 81

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Hair breakage rather than shedding from the root, visible as broken short hairs without the white telogen bulb, suggests a structural hair problem rather than a cycling problem and requires different investigation