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Antioxidant peptides derived from chia seeds: optimization, purification, identification, molecular mechanism analysis and experimental validation - ScienceDirect
Within the TME, high CHKA expression in tumor cells transforms them into metabolic choline sinks, depriving nearby immune cells, such as tumor-infiltrating lymphocytes (TILs), of choline needed for their own membrane synthesis, thereby contributing to immunosuppression (Li et al., 2025)
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