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Understanding the application requirements for a new substance in listed medicines | Therapeutic Goods Administration (TGA)
Either genetic or pharmacologic inhibition of TrxR1 activity induces Nrf2 without inducing oxidative stress, indicating that a part of the stress-sensing regulatory mechanism of Nrf2 is controlled by TrxR1 [49, 173–176]
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Annotations were refined using the Global Catalog of Microorganisms pipeline 1 (Shi et al., 2021), referencing key databases including SwissProt, MetaCyc (Jia et al., 2017
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