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In JEG-3 cells, HSP60 additionally participates in delivery of cholesterol to the metabolizing enzyme CYP11A1 (Monreal-Flores et al., 2017)
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The efficacy of uPAR-targeted CAR-T cells to remove senescent cells in vivo was investigated in different mice models with different age-related diseases, including cancer and liver fibrosis, and showed a significative efficiency
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