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These are research directions, not conclusions: the studies describe what was measured in non-clinical systems, and none of them establishes an outcome in humans

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Accordingly, we proposed to modify the langauge at § 414.1455(b)(3)(ii) and (b)(3)(vi) to make clear that the same timing requirements that for MIPS Targeted Reviews that are currently specified in at § 414.1385(a)(2) and (a)(5) also apply for purposes of QP Targeted Reviews