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The mustard seed extract was testified for APAP-induced toxicity in a hepatocellular carcinoma cell line (HepG2) and was found to have protective effects in both post and pretreatment models with a 20 mM APAP dose (Parikh et al., 2015)
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Additionally, probenecid may modulate urate binding by plasma proteins and influence uric acid secretion within the renal tubules
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