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A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men: safety, insulin-sensitivity, and lipid-mobilizing effects
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Mitochondrial beta-oxidation stimulation — AOD-9604 increases expression of beta-oxidation enzymes (CPT-1, acyl-CoA oxidase) in liver and adipocytes, directing released fatty acids toward energy combustion rather than re-storage (Heffernan 2001 Biochim Biophys Acta)
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