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However, robust long-term human data — for example on continuous use or drug interactions — is entirely absent

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The peptide was originally believed to be involved in sleep regulation because it appeared to induce slow-wave sleep in rabbits, but as that same source notes, "studies on the subject have been contradictory." DSIP has low molecular stability in vitro, with a half-life reported at about 15 minutes, attributed to a specific aminopeptidase-like enzyme