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Activation of Group I mGluR5 receptors, coupled to Gα q proteins, has been shown to acutely alter GLT-1 activity by increasing glutamate clearance in astrocytes (40) but chronic stimulation can lead to a reduction in astrocytic GLT-1 and GLAST levels resulting in reduced glutamate transport (35)
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It has also been claimed that this method makes it possible to analyze EXOs in tiny samples without the need for specialized reagents or costly equipment ( Cho et al
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