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The reactive intermediate of paracetamol is N-acetyl benzoquinone-imine (NABQI). The normal PCM dose produces (Mecapturic acid), through a reaction catalysed by enzyme called Glutathione-s-transferas
Some chemotherapeutics cause “coasting” of symptoms, the progressive worsening of neuropathy after cessation of treatment, and in severe cases CIPN can develop into an irreversible sensory neuron deficit
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[DOI] [PMC free article] [PubMed] 618.Ritthipichai, K
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