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(2015) proposed that translation of GGP mRNA is repressed because the interaction of the uORF-encoded peptide with ascorbate causes ribosomes to stall on the uORF and thereby blocks their progression to the AUG start of the GGP-coding sequence
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Conditions such as diabetes, obesity, or pre-existing spinal stenosis can extend recovery and make symptoms of sciatica harder to alleviate symptoms through conservative means alone
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