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The formation of a covalent link between a highly polar group, such as a glucose, sulfate, or the tripeptide glutathione, directly to a drug molecule or its phase I metabolite increases the hydrophilicity of the molecule and ultimate excretion in the urine or bile

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Research Findings Both component peptides have a body of preclinical and clinical research published primarily in Russian-language journals, with a growing number of English-language reviews and translational studies