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Selective deletion of Grk2 in vascular endothelium of mice also blunts the vasoconstriction induced by the α 1 -adrenergic receptor agonist phenylephrine and other vasoconstrictors (serotonin, oxytocin, and KCl) [59]
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749,750,751,752 Moreover, macrophages significantly influence liver aging, particularly through TGF-β signaling
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