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(2021) specifically stated: “An additional challenge for biofortification is the tendency of rising CO2 concentrations to diminish the concentrations of multiple nutrients concomitantly (Loladze (2014a) and (2014b)) in contrast to biofortification that targets only one or a few selected nutrients.” Further, biofortification cannot address the issue of increased toxin levels in crops associated with elevated CO2 and CO2-induced warming
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