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A 2012 review by Pickart, Vasquez-Soltero, and Margolina analyzed Broad Institute Connectivity Map data from PC3 and MCF7 cell lines treated with GHK at 1 μM, identifying 268 genes with increased expression and 167 genes suppressed
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Pharmacokinetics: The only direct PK study Awosemo, Neelakantan, and colleagues, publishing in the Journal of Pharmaceutical and Biomedical Analysis in 2021, developed and validated an LC-MS/MS assay to measure 5-amino-1-methylquinolinium concentrations in rat plasma and characterized the compound's oral bioavailability in rats
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