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Hormones such as GH, insulin, and thyroid hormones can modulate IGF-2 expression (42, 43)

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It can also be noted the superiority of the combined use of LLLT and TENS in improving orgasmic function, by 30.5% ( t = 3.38, p -value = 0.002, Cohen’s d = 1.12), in improving sexual desire, by 30.9% ( t = 4.64, p -value = 0.0001, Cohen’s d = 1.60), and in improving overall sexual satisfaction, by 33.3% ( t = 3.33, p -value = 0.002, Cohen’s d = 1.18), compared to LLLT results