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Alternative Medicine Review believes that exploring the possibilities of these treatments is critical to ensuring both clinicians and patients understand their options and make informed choices regarding care
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In preclinical models, ABT-737 showed high affinity for BCL-2, BCL-XL, and BCL-W and induced regression of solid tumors and lymphomas in mice, confirming that pharmacological engagement of the BH3 groove is sufficient to activate the intrinsic apoptotic pathway [129,130,131]
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