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In a rat model of reversible arterial occlusion simulating cerebral ischemia, pre-treatment with SIN (90 mg/kg) via tail vein injection provided neuroprotection through an-ti-inflammatory effects, amelioration of acidosis, improvement of energy metabolism, and suppression of ASIC-1a levels (100)
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The connection between SRB and H 2 S blood concentration is observational at best, as no study has reported blood H 2 S concentrations in the setting of neuroinflammation and dysbiosis
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