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Morning injection (6 to 9 AM) gives you: - Coverage through the inflammatory afternoon buildup - No interference with sleep (KPV is not stimulating, but injections can break the wind-down routine) - Alignment with most injection training (empty stomach, shower after, clean needle routine) - Predictable absorption (cortisol peak supports the anti-inflammatory signal) Evening injection is acceptable when: - You are using KPV specifically for nocturnal joint pain or inflammation - You inject other peptides in the morning and want to space the protocol - Your work schedule makes morning injections impractical At the standard 200 to 500 mcg daily subcutaneous range, splitting the injection between morning and night adds logistics without adding benefit