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Consistently, ML364 intervention downregulated the transcription of profibrotic genes, namely Col1a1 , Col3a1, Fn1 , Eln , Ccn2 , and Acta2 , in mouse kidneys following injury (Fig
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The T-cell marker CD3 and the Th1 cytokine interferon-γ are elevated in perigonadal fat from ovariectomized female mice (39), suggesting that the absence of E2 promotes immune cell inflammation
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