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Domain Structure and Signaling Components of HGF-MET Pair Hepatocyte growth factor is produced and secreted as pro-HGF, representing the inactive precursor, and then activated by proteolytic processing in the extracellular milieu (Naldini et al., 1992)
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However, what causes such an increase in the oxidative damage of the macromolecules and whether male and female have the same susceptibility are not clear
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