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Tissue was pulverized with a Covaris CPO2 CryoPrep Automated Dry Pulverizer (Covaris, Woburn, MA) and RNA was extracted with Trizol (Invitrogen)
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Together, these results indicate that FOXO4-DRI can reduce cellular senescence and counteract hair loss and general frailty in fast aging Xpd TTD/TTD mice
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